WebJun 10, 2024 · 2024 年发现的chromsfork 调控,通过提高停顿复制叉周围的染色质结构紧密程度,也是为了阻挡复制解旋酶脱离复制叉,以维持复制叉稳定 (Feng et al. (2024), PNAS, 116(29):14563- 14572)。 图 2. 磷酸化复制解旋酶CMG 里的Cdc45 亚基,深度降低复制解旋酶活性,阻止复制解旋酶与 DNA 聚合酶分开,从而稳定停顿复制叉。... WebDec 1, 2024 · Chromsfork functions in parallel with checkpoint for the stability of stalled replication forks [45]. Replication fork stalling gives rise to a situation in which the …
Replication fork stalling elicits chromatin compaction for the ...
WebJul 16, 2024 · Stalling forks require strict cellular regulations to prevent fork collapse. However, the mechanism underlying these cellular regulations is poorly understood. In … WebEditorial Board Member. Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA 19102, USA. Interests: DNA replication; DNA repair; genomic instability; cancer; aging. Special Issues, Collections and … can chemo help with stage 4 pancreatic cancer
Google Tasks Fork - Chrome Web Store - Google Chrome
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