Circeif4g3
WebResults Downregulated expression of circular RNA EIF4G3 (circEIF4G3; hsa_circ_0007991) was found in GC and was associated with poor clinical outcomes. Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of β-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. WebThe results showed that the expressions of circDDX17, Has_circ_0026344, circVAPA, circNSUN2, circACAP2, circACVRL1 and circEIF4G3 were regulated by 0.8 mmol/L ALO (p<0.001, Figure 3A). Through subsequent screening of target genes, we found that only circNSUN2 and miR-296-5p have targeted binding sites .
Circeif4g3
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Web正式实验上，团队构建了circEIF4G3敲低与过表达的细胞模型，通过体外功能实验（RNA-FISH、细胞增殖与迁移和侵袭检测、细胞凋亡检测）以及体内动物实验（免疫组织化学 … WebDec 13, 2024 · Gastric cancer (GC) is the third most common cause of cancer-related death worldwide. Advanced diagnosis and high rates of relapse and metastasis are associated with the poor prognosis of this disease. GC has a complex etiopathogenesis of which the underlying mechanisms remain to be explored.
WebAug 10, 2024 · The formation of a unique back-splice junction (BSJ) differentiates the circRNAs from their linear counterpart. CircRNAs are highly expressed in the central nervous system where many of them are regulated during development 1 – 3, inflammation 4, and also found to function as biomarkers in cancer 5 – 7. WebFeb 2, 2024 · Renal cell carcinoma (RCC) is one of the top ten tumors over the world. RCC is not sensitive to radiotherapy and chemotherapy. Therefore, it is necessary to find new targets for the treatment. CircRNAs are a special type of noncoding RNAs, which play important roles in many types of cancer. In this study, we found circ_000558 was …
WebJul 2, 2024 · Europe PMC is an archive of life sciences journal literature. WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ …
WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ …
WebOct 19, 2024 · CDR1as expression is known to be correlated with hepatic microvascular invasion in HCC tissue and hsa_circ_0000520 (circRPPH1), hsa_circ_0005075 (circEIF4G3), hsa_circ_0066444 (circADAMTS9), and hsa_circ_0001649 (circSRPRH) have all been shown to be expressed at different levels in HCC compared to adjacent normal … in xef2 xenon involves the hybridisation:WebDownload scientific diagram CircEIF4G3 functions as a miR-4449 sponge. (A) RIP assay was applied using Ago2 antibody in GC cells. The relative RNA level of circEIF4G3 was detected by qRT-PCR. in xef2 xef4 xef6 the number of lone pairsWebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ … inxee systems private limitedWebhsa_circEIF4G3_060. Last modified by: XXH Created Date: 4/29/2024 8:53:00 AM Other titles: 交集的circRNA Sheet2 ... onpoint credit union tigard oregonWebBackground: Circular RNAs (circRNAs), a new group of endogenous non-coding RNAs, plays a crucial role in various types of carcinomas. However, there is still limited … onpoint credit union scappooseWebCircEIF4G3 acts as a scaffold to promote δ-catenin ubiquitin degradation by TRIM25. (A) The expression of δ-catenin protein in GC cells with or without circEIF4G3 overexpression after treatment... inxenioWeb(A) Cell counting assays for control and circEIF4G3 overexpressing GC cells. (B) The impact of circEIF4G3 overexpression on GC cell proliferation was determined by cell colony formation assay. onpoint credit unions in portland oregon