Cisplatin function

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August undefined, 2024

WebWhat Cisplatin Is Used For: Treatment of advanced bladder cancer, metastatic ovarian cancer, and metastatic testicular cancer. Testicular, ovarian, bladder, head and neck, … WebMar 23, 2024 · Here, we postulated that systemically delivered rapamycin perfluorocarbon nanoparticles (PFC NP) could reach the injured kidneys at sufficient and sustained concentrations to mitigate cisplatin-induced acute kidney injury …

Cisplatin Monograph for Professionals - Drugs.com

WebThe cisplatin molecule binds with a protein on one side and the DNA molecule on the other. The protein is critical; it protects the cisplatin molecule from being removed by DNA repair mechanisms in the cell. New combination regimens are often tried in clinical trials, and it is common for newly … WebCisplatin is a chemotherapy medication used to treat a number of cancers. [2] These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, … photo chic eyeliner pencil

Targeted therapy for cisplatin‐resistant lung cancer via …

WebSep 1, 2024 · Cisplatin for injection is indicated for the treatment of advanced testicular cancer. Advanced Ovarian Cancer Cisplatin for injection is indicated for the treatment of … WebCisplatin has been a mainstay of cancer chemotherapy since the 1970s. Despite its broad anticancer potential, its clinical use has regularly been constrained by kidney toxicities. This review details those biochemical pathways and metabolic conversions that underlie the kidney toxicities. WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is … photo chicha

The cardioprotective effect of human glucagon-like peptide-1 …

Cisplatin in cancer therapy: molecular mechanisms of action

WebSep 15, 2024 · Cisplatin is a prescription medicine used to treat the symptoms of cancer in the testicles (Metastatic Testicular Tumors), bladder (Advanced Bladder Cancer) and … WebCisplatin stimulates production of reactive oxygen species and oxidative stress by depleting and inactivating glutathione and other related antioxidants. • Cisplatin induces both … photo chicago skylineWebJul 18, 2024 · For induction of remissions, a regimen of cisplatin, bleomycin, and vinblastine (with or without other antineoplastic agents) has been used. For treatment of disseminated disease, a regimen of cisplatin, bleomycin, and etoposide has been used. photo chic eyeliner

"WebMar 15, 2024 · Cisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head and neck cancers. Approximately 500,000 patients diagnosed annually with these cancer types in the United States could be candidates for treatment with cisplatin. " - Cisplatin function

Cisplatin function

Cisplatin - an overview ScienceDirect Topics

Webcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage … WebOct 3, 2024 · Unfortunately, some chemotherapies can also cause strokes, such as methotrexate, cisplatin, imatinib and more. Some agents, such as bevacizumab and sunitinib, intentionally target blood vessels since tumors often create new vessels to send nutrients to the abnormal growth. Unfortunately, side effects can include hemorrhage or …

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WebWhat is cisplatin? Cisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other … WebVarious recent studies have investigated (GLP-1R) role in cardiovascular diseases due to antiapoptotic and antioxidant effects. The current study aimed to investigate the curative …

WebFeb 16, 2016 · Cisplatin is standardly dosed in a three-weekly schedule of 100 mg/m 2 (total dose 300 mg/m 2) combined with standard RT [ 3, 6, 7, 9, 10 ]. However, a high-dose cisplatin regimen is associated with major toxic side effects (myelosuppression, neurotoxicity, ototoxicity, and nephrotoxicity). WebCisplatin(cis-dichlorodiammineplatinum)–platinum coordination complex is an effective chemotherapy against a wide spectrum of tumors such as testicular, head and neck, …

WebAug 6, 2014 · Cisplatin and other platinum derivatives are the most widely used chemotherapeutic agents to treat solid tumors including ovarian, head and neck, and testicular germ cell tumors. A known complication of … WebFeb 16, 2024 · Aluminum reacts with this drug, causing precipitate formation and a loss of potency. Monitoring: Peripheral blood counts should be monitored weekly. Liver function should be monitored periodically. Neurologic examination should be performed regularly. More about cisplatin Further information

WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

WebCisplatin is administered to cancer patients intravenously as a sterile saline solution (that is, containing salt—specifically, sodium chloride). Once cisplatin is in the bloodstream, it … photo chicandierWebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different … photo chickenWebCisplatin has been a mainstay of cancer chemotherapy since the 1970s. Despite its broad anticancer potential, its clinical use has regularly been constrained by kidney toxicities. … how does cholangiocarcinoma cause deathWebFeb 16, 2024 · What is cisplatin? Cisplatin is used together with other cancer drugs to treat bladder cancer, testicular cancer, or ovarian cancer. Cisplatin may also be used for … how does cholelithiasis affect the liverWebCisplatin has disturbed mitochondrial function and dynamics, dysregulate redox status and induced mitophagy and apoptosis, in the other hand semaglutide treatment has normalized dysregulated mitochondrial function and dynamics, … photo chicken poxWebTMEPAI was known to be induced by TGF-β/Smad signaling and have tumorigenic functions that converting TGF-β from tumor suppressor to tumor promoter and inducing epithelial–mesenchymal transition (EMT). ... (IC50) of several anti-cancers: doxorubicin, cisplatin, paclitaxel, and bicalutamide in the presence of TGF-β treatment.Results: KO ... photo cheyenneWebCisplatin for injection has been administered at 75 mg/m. 2 . to 100 mg/m. intravenously per cycle once every 3 to 4 weeks on Day 1. Other doses and combination regimens have … how does cholelithiasis cause pancreatitis