WebHere, we demonstrate that the crystalline sponge method provides an effective way to crystallographically determine the absolute configuration of organic compounds bearing chiral quaternary carbons (including tetra-substituted ones) that are synthesized by recently developed enantioselective catalytic reactions. Introduction WebA detailed set of synthetic and crystallographic guidelines for the crystalline sponge method based upon the analysis of expediently synthesized crystal sponges using third-generation synchrotron radiation are reported. The procedure for the synthesis of the zinc-based metal–organic framework used in initial crystal sponge reports has been modified to …

Chinese Chemical Society

WebThe crystalline sponge method is a recently developed technique for single crystal diffraction (SCD) studies that does not require crystallization of the samples. 3 By soaking guests into porous coordination networks (crystalline sponges), the guests are oriented for SCD study. 4 For the practical use of this method, a detailed protocol 5 and … WebSep 17, 2024 · The crystalline sponge method entails the elucidation of the (absolute) structure of molecules from a solution phase using single‐crystal X‐ray diffraction and eliminates the need for... kangs costcutter leamington spa

CRYSTALLINE SPONGE METHOD FOR SYNTHETIC AND …

WebJul 13, 2024 · Ultra-stable porous organic molecular framework as a crystal sponge to achieve rapid molecular structure determination July 13, 2024. An Ultrastable π–π Stacked Porous Organic Molecular Framework as a Crystalline Sponge for Rapid Molecular Structure Determination. WebSep 17, 2024 · The crystalline sponge method entails the elucidation of the (absolute) structure of molecules from a solution phase using single-crystal X-ray diffraction and eliminates the need for crystals of the target compound. ... The host crystal that is most often used decomposes in protic or nucleophilic solvents, or when guest molecules with … WebThe Crystalline Sponge (CS) method is an approach to obtain single-crystal X-ray structures of compounds, that are difficult or impossible to crystallize, for example … lawn mower tubes 20x8x8