WebRefractile crystalline deposits may also be a manifestation of drug toxicity like the antineoplastic agent tamoxifen, the anesthetic methoxyflurane and the oral tanning … Webrevealed refractile crystalline retinal deposits in both maculae (Figure 1, A and B). The appearances were consistent with a diagnosis of crystalline/tamoxifen retinopathy and treatment was discontinued. At …

Crystalline retinopathy: Unifying pathogenic pathways of disease

WebJan 19, 2024 · Commonly included in the list of possible (often rare) causes for this condition are: age-related macular degeneration, talc retinopathy, retinal emboli, tamoxifen retinopathy, canthaxanthin retinopathy, methoxyflurane retinopathy, hyperoxaluria, renal-related retinopathy (cilioretinopathies, Alport’s, cystinosis) retinitis punctata albescens, … Web“Tamoxifen has long been known to cause eye problems, including dryness, irritation, cataracts, and deposits in the retina, in the area of the … oommen chandys son chandy oommen

Common Medications That May Be Toxic to the Retina

WebCrystalline retinopathy is characterized by intraretinal crystalline deposits that, according to their etiology, can be localized in the macular area or, indeed, be found in the entire retina. These deposits can be associated or not to … WebDec 12, 2024 · Tamoxifen is mainly a prodrug as two of its many metabolites, notably 4-hydroxy-N-desmethyltamoxifen (endoxifen) and also 4-hydroxytamoxifen (4-OHT), are known to have greater affinity for the estrogen receptor than tamoxifen itself. Routine therapeutic dosage starts at 20 mg daily and can be increased up to 40 mg daily. WebJun 12, 2014 · Tamoxifen is a retinal toxin in its own right, although most cases of tamoxifen retinopathy were reported early in the history of the drug when higher … oommen philip modayil