Phospho-4ebp1

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August undefined, 2024

WebApr 1, 2024 · We also engineered a mutant 4E-BP1 that cannot be phosphorylated by mTOR resembling de-phospho-Thr46-4E-BP1, and generated HNSCC cells expressing this mutant in a tetracycline-inducible fashion. Expression of 4E-BP1 M was sufficient to disrupt the function of the translation–initiation complex, and resulted in tumor regression in HNSCC ... Web实验用到的供体是Thr46（铽标记的anti-phospho-4EBP1），受体是绿色荧光标记的4EBP1，是mTOR下游信号通路的蛋白，有活性的mTOR能磷酸化4EBP1，使之与供体结合。如果mTOR活性受到抑制，供体受体距离不能达到荧光能量转移的要求，则在515nm处与485nm处的信号比值增大。

4E-BP Antibody Sampler Kit Cell Signaling Technology

WebPhospho-4EBP1 (Thr37, Thr46) Polyclonal Antibody Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. … WebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 and 4E-BP3 when phosphorylated at equivalent sites. Non-specific staining has been observed in mitotic cells by immunofluorescence Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb song that says i get my peaches from georgia

GSK-3 directly regulates phospho-4EBP1 in renal cell …

WebJul 6, 2024 · 北京百奥创新科技有限公司是一家专注于生命科学的科技企业，由在国内科研试剂领域有着丰富从业经验的技术团队和管理团队组建而成，专营进口生物试剂，科学仪器，实验消耗品等。 WebPhospho-mTOR and phospho-4EBP1 in endometrial adenocarcinoma: association with stage and grade in vivo and link with response to rapamycin treatment in vitro p-mTOR expression was associated with nuclear p-4EBP1 expression (P = 0.02), and was more frequent in tumors extending ouside the uterine corpus (P = 0.011). WebPhospho-4E-BP1 (Ser65) Antibody detects endogenous levels of 4E-BP1 when phosphorylated at serine 65. This antibody has been shown to also recognize 4E-BP1 … song that says in the year 2020

Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb

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WebTranslation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation (1). Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity ... WebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. small group israel toursWeb山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒；英文名称： pdgf-bb elisa kit ；实验名称：山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒；实验别名：山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒 48t/96t ；规格： 48t/96t 报价山羊血小板衍生生长因子bb(pdgf-bb)elisa试剂盒实验目的：本试剂盒仅供研究使用 ... song that says n word a lot

"WebJan 2, 2024 · Here we demonstrate that rapamycin-insensitive mTORC1 signaling via 4E-BP1 is a critical pathway for TGF-β 1 stimulated collagen synthesis in human lung fibroblasts, whereas canonical PI3K/Akt... " - Phospho-4ebp1

Phospho-4ebp1

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WebPhospho-4EBP1 (Thr37, Thr46) Antibody (PA5-114544) in ICC/IF Immunocytochemistry analysis of Phospho-4EBP1 (Thr37, Thr46) in HeLa cells (heat shock treatment). Samples … WebJul 7, 2016 · GSK-3 differentially regulates 4EBP1 and S6RP phosphorylation in ACHN cells. a Changes in the phosphorylation levels of 4EBP1 and S6RP over time after treatment of AR-A014418 (25 μM) or rapamycin ...

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WebApr 14, 2024 · Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. We previously demonstrated that the mammalian target of rapamycin (mTOR) inhibitor rapamycin suppressed orofacial formalin injection-induced nociception; however, the … WebMolecular Cell, Vol. 12, 889–901, October, 2003, Copyright 2003 by Cell Press Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential

WebMay 19, 2015 · Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors PLoS One doi: 10.1371/journal.pone.0127123. eCollection 2015. Authors WebEu-phospho-4EBP1 (25 µL) Acc-phospho-4EBP1 (100 µL) 4EBP1 control lysate (200 µL) 5X Lysis Buffer 2 (5 mL) 10X TR-FRET Detection buffer (250 µL) 100X Phosphatase Inhibitor Cocktail (250 µL) Reactivity Human US $ 1,199.00 Add to cart BioAuxilium sells direct to Canada- and US-based customers only.

WebSep 11, 2024 · Glioblastoma is the most common malignant primary brain tumor, and it is one of the causes of cancer fatality in both adult and pediatric populations. Patients with glioblastoma require chemotherapy after surgical resection and radiotherapy. Therefore, chemotherapy constitutes a viable approach for the eradication of glioblastoma cells. In … WebOur 4EBP1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by …

WebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 …

WebApr 14, 2024 · Neuropathic pain caused by trigeminal nerve injury is a typical refractory orofacial chronic pain accompanied by the development of hyperalgesia and allodynia. … small-group irish tours dublinWebPhospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46. This antibody may cross-react with 4E-BP2 … small group italy toursWebKeyTec®TR-FRET Phospho-STAT4 (Y693) Kit : KeyTec®TR-FRET Phospho-STAT5 (Y694/Y699) Kit : KeyTec®TR-FRET Total STAT5 Kit : KeyTec®TR-FRET Phospho-STAT6 (Y641) Kit : KeyTec®TR-FRET Total STAT6 Kit : KeyTec®TR-FRET Phospho-4EBP1 (T37/T46) Kit : KeyTec®TR-FRET Total 4EBP1 Kit : KeyTec®TR-FRET Phospho-BTK … song that says it\u0027s your birthday mercedesWeb运动和PI3K阻断剂对大鼠骨骼肌mTOR及下游信号的作用研究,sd大鼠,大鼠阅读答案,wistar大鼠,大鼠解剖图,大鼠翻译,大鼠蒲松龄,大鼠十二脂肠插管,大鼠固定器,大鼠代谢笼 song that says stuck in the friend zoneWebMay 28, 2014 · The phosphorylation status of S6RP or 4EBP1 is thus often used as a measure of mTOR activity in laboratory studies. However, whether these mTOR-associated molecules, namely AKT, mTOR, S6RP and 4EBP1, could be used as predictors of efficacy for everolimus treatment remained elusive and need further investigations. small group italy tours 2022WebListed below are anti-4EBP1 antibodies from multiple suppliers. 4EBP1 is a reported alias name for the human gene EIF4EBP1, or 'eukaryotic translation initiation factor 4E binding … small group italian toursWebThe aim of this study was to evaluate the role of phosphorylated 4EBP1 (p4EBP1) in primary renal cell carcinoma (RCC) as a biomarker in metastatic RCC (mRCC) and non-mRCC … song that says run